Product Description
Starazolin is a medicinal product intended for adults and children over 2 years of age, indicated for the symptomatic treatment of conditions accompanied by conjunctival swelling and redness caused by irritants such as dust, smoke, wind, bright light, chlorinated water, cosmetics, and contact lenses. It can also be used in allergic eye conditions, such as hay fever and pollen allergy. Starazolin relieves burning, itching, soreness, excessive tearing, and irritation.
Indications
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Conjunctival swelling and redness
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Allergic eye conditions, including hay fever and pollen allergies
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Eye fatigue
Composition (per 1 ml)
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Active ingredient: Tetryzoline hydrochloride 0.5 mg
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Excipients: sodium chloride, disodium edetate, benzalkonium chloride, borax (sodium tetraborate), boric acid, highly purified water
Pharmacological Action
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Reduces conjunctival redness and swelling
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Relieves burning, itching, soreness, excessive tearing, and irritation
Dosage and Administration
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Always use as directed in the patient leaflet or by a physician or pharmacist
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Adults and children over 2 years: 1–2 drops in the conjunctival sac, 2–3 times daily
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Apply locally to the conjunctival sac
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Do not use while wearing contact lenses
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The product may be used within 28 days of first opening
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Starazolin is sterile. Do not touch the dropper tip; close the bottle tightly after use
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For single-use containers: detach the vial, twist off the extended tip, discard the first two drops, and instill the remaining drops into the eye(s). Remaining content cannot be reused
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Remove contact lenses before application and reinsert approximately 15 minutes after instillation
Contraindications
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Hypersensitivity to tetryzoline or any other ingredients
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Children under 2 years
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Glaucoma, particularly narrow-angle glaucoma, or other serious ocular conditions
Storage
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Store at temperatures up to 25°C, in a place out of sight and reach of children
Adverse Reactions
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Overuse (excessive duration or frequency) may cause eye pain or burning, reactive redness, blurred vision, conjunctival irritation, or, rarely, pupil dilation
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Systemic sympathomimetic effects (e.g., elevated blood pressure, increased heart rate, increased respiration) may rarely occur
Common (affecting fewer than 1 in 10 patients):
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Reactive redness
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Burning of mucous membranes
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Dry mucous membranes
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Systemic effects (palpitations, headache, tremor, weakness, excessive sweating, increased blood pressure)
Very Rare (affecting fewer than 1 in 10,000 patients):
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Excessive conjunctival keratinization with lacrimal duct obstruction and excessive tearing
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Blurred vision, conjunctival irritation, and, rarely, pupil dilation may occur. Special caution is needed for newborns and children under 2 years due to potential systemic absorption. Significant adverse effects involve the central nervous system, such as increased blood pressure, heart rhythm disturbances, tachycardia, tachyarrhythmia, or reactive bradycardia.
Interactions
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Inform your doctor or pharmacist about all medicines being taken or planned
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Concurrent use with MAO inhibitors, tricyclic antidepressants, guanethidine, or reserpine may increase blood pressure; use only under medical supervision
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Concurrent use with anesthetics, insulin, atropine sulfate, or propranolol may enhance cardiovascular effects
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Maintain a 15-minute interval when using other eye drops
Warnings and Precautions
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Consult a doctor or pharmacist before use
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Discontinue if inflammation worsens during treatment
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Intended for moderate conjunctival irritation only
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Not recommended for use during eye infections, corneal damage, or severe pain
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If no improvement occurs after 2 days, discontinue and seek medical advice
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Prolonged use may cause secondary irritation, reactive redness, burning sensations, and degenerative changes due to chronic hypoxia of the ocular mucosa
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Exercise caution in patients with cardiovascular disease, hypertension, adrenal pheochromocytoma, diabetes, or hyperthyroidism, especially if taking MAO inhibitors or other medications affecting blood pressure
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Discontinue use of soft contact lenses during treatment
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Recommended doses do not usually cause pupil dilation; overuse may increase risk, particularly in patients with light-colored irises
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Seek immediate medical advice if experiencing severe eye pain, headache, vision loss, sudden appearance of floaters, sudden eye redness, photophobia, or double vision
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Not effective for late-type allergic reactions (e.g., contact conjunctivitis or eyelid dermatitis)
Use in Children and Adolescents
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Long-term use should be avoided, especially in children
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Contraindicated in children under 2 years
Pregnancy
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Consult a doctor before use if pregnant, breastfeeding, or planning pregnancy
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Safety of tetryzoline in pregnancy has not been established
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Use in pregnancy only if clearly necessary and prescribed by a physician
Breastfeeding
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No data on tetryzoline excretion in breast milk
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Use with caution and under medical advice
Driving and Operating Machinery
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No direct effect on ability to drive or operate machinery, but eye inflammation, pupil dilation, or blurred vision may temporarily impair psychomotor function
Contains Benzalkonium Chloride
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Each ml contains 0.1 mg benzalkonium chloride
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May be absorbed by soft contact lenses and cause discoloration
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Remove lenses before use and wait at least 15 minutes before reinsertion
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May irritate eyes, especially in patients with dry eye syndrome or corneal disorders
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Seek medical advice if abnormal sensations, stinging, or eye pain occur